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Photonics, Vol. 8, Pages 441: Research on X-ray Fluorescence Enhanced Fluoroscopy Imaging Technology

Photonics doi: 10.3390/photonics8100441

Zhenyao Yan
Liang Li
Rui Qiu
Zhiqiang Chen

Chest X-ray fluoroscopy is a commonly used medical imaging method, which has a wide range of applications in the diagnosis of lung diseases and other fields. However, due to low contrast and relatively close linear attenuation coefficients, some early small lesions are difficult to detect in time. Using the X-ray fluorescent effect of high atomic number metal elements and metal atom-containing agents that can be enriched in the lesion, the fluoroscopy signal and the fluorescent signal emitted by the metal atoms can be detected at the same time during the fluoroscopy, and the images of the two can be integrated, which can theoretically enhance the contrast between the lesion and the surrounding tissue. Based on GEANT4, this paper conducts Monte Carlo simulations to explore the feasibility and enhancement effects of three enhancement schemes: the pencil beam spot scanning method, cone-beam collimation method, and slit scanning method, and discusses the specific geometric structure and material selection.

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